publications

2023

  1. RASopathy_distance.png
    Refining nosology by modelling variation among facial phenotypes: the RASopathies
    Harold Matthews, Michiel Vanneste, Kaitlin Katsura, and 8 more authors
    Journal of Medical Genetics, 2023
  2. Precise modulation of transcription factor levels identifies features underlying dosage sensitivity
    Sahin Naqvi, Seungsoo Kim, Hanne Hoskens, and 8 more authors
    Nature Genetics, 2023
  3. Quantification and visualization of the tooth extraction effects on face with spatially dense geometric morphometrics
    Yi Fan, Zhiyu Liu, Gui Chen, and 6 more authors
    Orthodontics & Craniofacial Research, 2023
  4. Exploring regional aspects of 3D facial variation within European individuals
    Franziska Wilke, Noah Herrick, Harold Matthews, and 7 more authors
    Scientific Reports, 2023
  5. Using data-driven phenotyping to investigate the impact of sex on 3D human facial surface morphology
    Harold S Matthews, Soha Mahdi, Anthony J Penington, and 6 more authors
    Journal of Anatomy, 2023
  6. Influence of age and diet consistency on the oral muscle pressure of orthodontically treated and untreated subjects with normal occlusion and comparison of their 3D facial shape
    Amit Arvind Rajbhoj, Harold Matthews, Kaat Doucet, and 4 more authors
    Clinical Oral Investigations, 2023
  7. Ulnar shape of extant primates: Functional signals and covariation with triquetrum shape
    Marie JM Vanhoof, Lorenzo Galletta, Harold Matthews, and 2 more authors
    American Journal of Biological Anthropology, 2023
  8. Assessing univariate facial phenotyping approaches in GWAS
    Meng Yuan, Seppe Goovaerts, Michiel Vanneste, and 8 more authors
    In 56th annual European Human Genetics Conference 2023, Date: 2023/06/10-2023/06/13, Location: Glasgow, Scotland, UK, 2023
  9. Joint multi-ancestry and admixed GWAS on 3D facial shape derived from MRI
    Seppe Goovaerts, Hanne Hoskens, Harold Matthews, and 8 more authors
    In ESHG meeting 2023, Location: Glasgow, UK, 2023
  10. A statistical shape model for estimating missing soft tissues of the face in a black South African population
    Helene Francia Swanepoel, Harold S Matthews, Peter Claes, and 2 more authors
    Journal of Prosthodontics, 2023
  11. Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population
    Michiel Vanneste, Hanne Hoskens, Seppe Goovaerts, and 8 more authors
    bioRxiv, 2023

2022

  1. static_and_motion.jpg
    Static and motion facial analysis for craniofacial assessment and diagnosing diseases
    Harold Matthews, Guido Jong, Thomas Maal, and 1 more author
    Annual Review of Biomedical Data Science, 2022
  2. Facial asymmetry assessment in skeletal Class III patients with spatially-dense geometric morphometrics
    Yi Fan, Wei He, Gui Chen, and 5 more authors
    European Journal of Orthodontics, 2022
  3. Automated assessment of mandibular shape asymmetry in 3-dimensions
    Yi Fan, Yungeng Zhang, Gui Chen, and 8 more authors
    American Journal of Orthodontics and Dentofacial Orthopedics, 2022
  4. Nasal characteristics in patients with asymmetric mandibular prognathism
    Yi Fan, Gui Chen, Wei He, and 5 more authors
    American Journal of Orthodontics and Dentofacial Orthopedics, 2022
  5. Multi-scale part-based syndrome classification of 3D facial images
    Soha Sadat Mahdi, Harold Matthews, Nele Nauwelaers, and 8 more authors
    Ieee Access, 2022
  6. Objective 3D facial phenotyping in Cri-du-Chat Syndrome
    Michiel Vanneste, Harold Matthews, Yoeri Sleyp, and 8 more authors
    In Joint BeSHG/NVHG meeting 2022, Date: 2022/04/20-2022/04/22, Location: Bruges Meeting & Convention Centre, 2022
  7. The potential of 3D facial analysis to recognize monogenic autism in the spectrum
    Yoeri Sleyp, Harold Matthews, Michiel Vanneste, and 7 more authors
    In Joint BeSHG/NVHG Meeting 2022, Date: 2022/04/20-2022/04/22, Location: Bruges Meeting & Convention Centre, 2022
  8. A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis
    Jaaved Mohammed, Neha Arora, Harold S Matthews, and 8 more authors
    bioRxiv, 2022
  9. OBJECTIVE STUDY OF FACIAL DYSMORPHISM USING SPATIALLY DENSE 3D FACIAL PHENOTYPING
    Michiel Vanneste, Harold Matthews, Peter Claes, and 1 more author
    In 32nd European meeting on Dysmorphology, Date: 2022/09/14-2022/09/17, Location: Snat Joan de Déu Auditorium, Barcelona, Spain, 2022
  10. Age-and sex-related differences in 3D facial shape and muscle pressure in subjects with normal occlusion
    Amit Arvind Rajbhoj, Harold Matthews, Kaat Doucet, and 4 more authors
    Computers in Biology and Medicine, 2022
  11. Age-Related Changes in Facial Soft Tissues and Muscle Pressure
    Amit Arvind Rajbhoj, Harold Matthews, Kaat Doucet, and 4 more authors
    In Pan European Region-International Association of Dental Research (PER-IADR), Date: 2022/09/15-2022/09/17, Location: Marseille, France, 2022
  12. A 3D Clinical Face Phenotype Space of Genetic Syndromes using a Triplet-Based Singular Geometric Autoencoder
    Soha S Mahdi, Harold Matthews, Michiel Vanneste, and 8 more authors
    bioRxiv, 2022

2021

  1. growth_curves.png
    Large-scale open-source three-dimensional growth curves for clinical facial assessment and objective description of facial dysmorphism
    Harold S Matthews, Richard L Palmer, Gareth S Baynam, and 8 more authors
    Scientific reports, 2021
  2. An exploration of adolescent facial shape changes with age via multilevel partial least squares regression
    Damian JJ Farnell, Stephen Richmond, Jennifer Galloway, and 6 more authors
    Computer methods and programs in biomedicine, 2021
  3. Impact of low-frequency coding variants on human facial shape
    Dongjing Liu, Nora Alhazmi, Harold Matthews, and 8 more authors
    Scientific Reports, 2021
  4. Automatic 3D dense phenotyping provides reliable and accurate shape quantification of the human mandible
    Pieter-Jan Verhelst, H Matthews, L Verstraete, and 8 more authors
    Scientific Reports, 2021
  5. 3D analysis of facial morphology in Dutch children with cancer
    Floor AM Postema, Harold Matthews, Saskia MJ Hopman, and 7 more authors
    Computer Methods and Programs in Biomedicine, 2021
  6. Determination of pre-arthropathy scapular anatomy with a statistical shape model: part I—rotator cuff tear arthropathy
    Filip Verhaegen, Alexander Meynen, Harold Matthews, and 3 more authors
    Journal of Shoulder and Elbow Surgery, 2021
  7. Automated landmarking for palatal shape analysis using geometric deep learning
    Balder Croquet, Harold Matthews, Jules Mertens, and 8 more authors
    Orthodontics & Craniofacial Research, 2021
  8. Exploring palatal and dental shape variation with 3D shape analysis and geometric deep learning
    Nele Nauwelaers, Harold Matthews, Yi Fan, and 8 more authors
    Orthodontics & Craniofacial Research, 2021
  9. Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations
    Chenxing Liu, Myoung Keun Lee, Sahin Naqvi, and 8 more authors
    PLoS genetics, 2021

2020

  1. pitfalls_and_promise.png
    Pitfalls and promise of 3-dimensional image comparison for craniofacial surgical assessment
    Harold S Matthews, Jonathan A Burge, Pieter-Jan R Verhelst, and 3 more authors
    Plastic and Reconstructive Surgery Global Open, 2020
  2. Accurate reconstructions of pelvic defects and discontinuities using statistical shape models
    Alexander Meynen, Harold Matthews, Nele Nauwelaers, and 3 more authors
    Computer methods in biomechanics and biomedical engineering, 2020
  3. Facial morphological changes following denture treatment in children with hypohidrotic ectodermal dysplasia
    Meili Ding, Yi Fan, Man Qin, and 5 more authors
    Pediatric Dentistry, 2020
  4. 3D assessment of mandibular skeletal effects produced by the Herbst appliance
    Yi Fan, Paul Schneider, Harold Matthews, and 7 more authors
    BMC oral health, 2020
  5. Comparison for Craniofacial Surgical Assessment
    Harold S Matthews, Jonathan A Burge, Pieter-Jan R Verhelst, and 3 more authors
    2020

2019

  1. Quantification of age-related changes in midsagittal facial profile using Fourier analysis: a longitudinal study on Japanese adult males
    Ashraf I Shaweesh, Harold Matthews, Anthony Penington, and 2 more authors
    Forensic science international, 2019
  2. Quantification of mandibular sexual dimorphism during adolescence
    Yi Fan, Anthony Penington, Nicky Kilpatrick, and 5 more authors
    Journal of anatomy, 2019
  3. MeshMonk: Open-source large-scale intensive 3D phenotyping
    Julie D White, Alejandra Ortega-Castrillón, Harold Matthews, and 8 more authors
    Scientific reports, 2019
  4. Marker-based watershed transform method for fully automatic mandibular segmentation from CBCT images
    Yi Fan, Richard Beare, Harold Matthews, and 6 more authors
    Dentomaxillofacial radiology, 2019

2018

  1. Estimating age and synthesising growth in children and adolescents using 3D facial prototypes
    Harold Matthews, Anthony Penington, John Clement, and 3 more authors
    Forensic science international, 2018
  2. Facial morphology and growth following surgery for congenital midline cervical cleft patients
    Y Fan, H Matthews, N Kilpatrick, and 3 more authors
    International Journal of Oral and Maxillofacial Surgery, 2018
  3. Modelling 3D craniofacial growth trajectories for population comparison and classification illustrated using sex-differences
    Harold S Matthews, Anthony J Penington, Rita Hardiman, and 4 more authors
    Scientific reports, 2018
  4. Mapping the Spectrum of Prenatal Alcohol Effects with Dense Surface Models of the Face and Brain
    Harold Matthews, Evelyne Muggli, Jane Halliday, and 1 more author
    Alcoholism: Clinical and Experimental Research, 2018

2017

  1. Association between prenatal alcohol exposure and craniofacial shape of children at 12 months of age
    Evelyne Muggli, Harold Matthews, Anthony Penington, and 8 more authors
    JAMA pediatrics, 2017
  2. Prenatal alcohol exposure and facial shape of one-year old children: no amount of alcohol is without consequence
    Evi Muggli, Harold Matthews, Anthony Penington, and 8 more authors
    Journal of Paediatrics and Child Health, 2017

2016

  1. Spatially dense morphometrics of craniofacial sexual dimorphism in 1-year-olds
    Harold Matthews, Tony Penington, Ine Saey, and 3 more authors
    Journal of anatomy, 2016

2012

  1. Independent effects of local and global binocular disparity on the perceived convexity of stereoscopically presented faces in scenes
    Harold Matthews, Harold Hill, and Stephen Palmisano
    Perception, 2012
  2. Refractive error and monocular viewing strengthen the hollow-face illusion
    Harold Hill, Stephen Palmisano, and Harold Matthews
    Perception, 2012

2011

  1. Binocular disparity magnitude affects perceived depth magnitude despite inversion of depth order
    Harold Matthews, Harold Hill, and Stephen Palmisano
    Perception, 2011
  2. The dual diagnosis capability of residential addiction treatment centres: priorities and confidence to improve capability following a review process
    Harold Matthews, Peter J Kelly, and Frank P Deane
    Drug and Alcohol Review, 2011